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Title: Phenotypic Personalized Medicine
Originating Office: IAS
Speaker: Ho, Chih-Ming
Issue Date: 14-Apr-2016
Event Date: 14-Apr-2016
Group/Series/Folder: Record Group 8.15 - Institute for Advanced Study
Series 3 - Audio-visual Materials
Location: 8.15:3 EF
Notes: IAS distinguished lecture.
Title from opening screen.
Abstract: To address the need for the systematic optimization of personalized treatment for a broad spectrum of physiological disorders, the speaker and his collaborators have developed a paradigm shift concept that they have termed Feedback System Control (FSC). FSC is an experimental/analysis platform that efficiently calibrates the adaptability of patient physiology towards therapeutic stimuli. Based on an experimental landscape of patient-specific phenotypic mapping, optimal drug-dose combinations can be identified from an almost infinitely large parameter space. FSC can subsequently provide unprecedented control and actionable insight into the dynamic nature of the patient body to enable directed phenotypic outcomes for transformative applications in Phenotypic Personalized Medicine (PPM). FSC based PPM is mechanism-independent and indication-agonistic. PPM platform has been successfully applied to more than 20 indications including organ transplants, cancers and infectious diseases.
Prof Chih-Ming Ho received his PhD from the Johns Hopkins University and holds the Ben Rich-Lockheed Martin Chair Professor and Distinguished Professor in the UCLA School of Engineering. He served as the UCLA Associate Vice Chancellor for Research from 2001-2005.
In 1997, Prof Ho was inducted as a member of the US National Academy of Engineering. In 1998, he was elected as an Academician of Academia Sinica. He is also a Fellow of the American Physical Society, American Institute of Aeronautics and Astronautics as well as American Institute for Medical and Biological Engineering. Prof Ho holds nine honorary chair professorships including the Einstein Professorship from the Chinese Academy of Sciences. He has delivered 18 named distinguished lectures and presented over 130 keynote talks in international conferences. He is ranked by ISI as one of the top 250 most cited researchers worldwide in the entire engineering category. He was awarded a Doctor of Engineering honoris causa from the Hong Kong University of Science and Technology in 2014.
Duration: 78 min.
Appears in Series:8.15:3 - Audio-visual Materials
Videos for Public -- Distinguished Lectures