Epigenetic Mechanisms of Stem Cell Aging and Rejuvenation

Abstract

[evdate 2016-01-29] IAS distinguished lecture.

Title from opening screen.

Prof Thomas Rando received his PhD in Cell Biology from Harvard University in 1987. He has been with the Stanford University since 1991, starting as a postdoctoral fellow in Molecular Pharmacology up to 1994, and currently Professor of Neurology and Neurological Sciences and Director of the Glenn Laboratories for the Biology of Aging at Stanford University. He is also Director of the Rehab R&D Center of Excellence of the Veterans Affairs Medical Center.

Prof Rando’s main areas of research include stem cell biology (myogenic lineage progression, cell fate determination, asymmetric cell divisions, notch signaling, Wnt signaling), muscle stem cell aging (epigenetic determinants, local and systemic influences, roles in age-related decline in regeneration and age-related atrophy), muscular dystrophies (disease pathogenesis, biomarkers and non-invasive imaging), tissue engineering (artificial scaffolds, regenerative therapies) and basic muscle cell biology (myogenic differentiation, muscle development).

Prof Rando received numerous awards including the MERIT Award from the US National Institute on Aging, the Director’s Pioneer Award, and the Transformative Research Award from US National Institutes of Health, etc.

Duration: 67 min.