|Title:||Molecular Chaperones: The Cellular Machinery of Protein Folding and its Implications in Human Disease|
|Group/Series/Folder:||Record Group 3.8 - Office of University Development and Public Affairs|
Series 6 - Audio-visual Materials
|Location:||3.8:6 box 6.3.5|
|Notes:||Shaw Prize Lecture in Life Science and Medicine.|
Title from opening screen: Shaw Prize Lecture in Life Science and Medicine 2012.
Abstract: Prof Franz-Ulrich Hartl illustrated the main principles of chaperone action in the cytosol. He also discussed the role of the chaperone network in controlling protein homeostasis and preventing the deposition of disease-causing protein aggregates. He speculated on the prospect of pharmacologically activating cellular chaperone capacity to combat neurodegenerative diseases.
Franz-Ulrich Hartl was born in 1957 in Essen, Germany. He currently holds the position of Director, Max Planck Institute of Biochemistry in Martinsried, Germany. Hartl received his MD from the University of Heidelberg in 1982 and did postgraduate work at Heidelberg, Munich and then Los Angeles from 1982 to 1990 before he began his independent work as a faculty member at the Sloan Kettering Research Institute where he remained from 1991 to 1997. During that time he held the position of Howard Hughes Investigator from 1994 to 1997 after which he returned to Germany to assume his current position. In addition to numerous prizes, including the Albert Lasker Award in Basic Medical Research, which he shared with Arthur L Horwich in 2011, and election to honorific societies, Hartl was elected as a Foreign Associate of the United States National Academy of Sciences in 2011.
Duration: 66 min.
|Appears in Series:||3.8:6 - Audio-visual Materials |
Videos for Public -- Distinguished Lectures