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|Title:||Darwinian Evolution as Front Propagation in Fitness Space|
|Group/Series/Folder:||Record Group 8.15 - Institute for Advanced Study|
Series 3 - Audio-visual Materials
|Location:||8.15:3 box 1.4|
|Notes:||Institute for Advanced Study Workshop: Evolution: Foundations, Fundamentals, and Disease. Session 2: Moving beyond classic darwinian evolution.|
Abstract: Motivated by experiments on laboratory‐scale evolution in both microorganisms and biomolecules, we introduce and study a class of multi‐locus evolution models, These models assume that the fitness landscape is smooth (not glassy). This can actually be justified for the case of evolving protein binding sites for DNA, but is otherwise an assumption that can be compared with the experimental data. For these models, the population advances via being dragged forward by its most fit members and can be quantitatively studied using ideas from the theory of non-equilibrium spatially‐extended processes. A key finding is the anomalously large dependence on population size and the related anomalously large usefulness of genetic recombination.
Duration: 64 min.
|Appears in Series:||8.15:3 - Audio-visual Materials|
Videos for Public -- Distinguished Lectures